They're mice. They fail every single time. Superman wins.
Pinky and the Brain could win in a fight against Superman.
Strengths
The Brain:
Super Genius
Pinky:
Ambivalent
Superman:
Virtually indestructible
Super Speed,
Super breath,
X-ray vision,
Heat vision.
weakness:
The Brain:
Ambivalent to the fact that Pinky continually fails.
Pinky:
Ambivalent
Superman:
Kryptonite,
Sun,
electricity.
The Brain could come up with marvelous ways to get rid of Superman.
Possibly the most obvious way to get rid of superman would be kryptonite laced sunscreen. Weakens him, and blocks out his power source.
I'd like to say The Brain would have done a thorough background check on Superman and learned that he has a habit of escaping death. The only logical way would be to separate his head from his body. But, I can't see the Brain actually doing that and Pinky would be too squeamish.
So most likely he would transfer superman's powers via electricity to Pinky.
Which of course would be his downfall in the end.
They're mice. They fail every single time. Superman wins.
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Yeah I have to go for superman on this one. Superman isn't an idiot, he's not going to sit there and say "hey this sunscreen hurts like kryptonite" and keep putting it on. One of the great things about Pinky and the Brain is they always fail. No matter how far they take their plan it always backfires or they sabotage themselves.
Superman for the win.
I say brain, he's got spielberg behind him, and warner brothers wouldn't risk pissing him off.
I got to admit, this would be an awesome throw down....
I'll go with Superman, only because P and B have failed to show me they can execute a plan to fruition. But there's always tomorrow.....
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